SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) Peptide
SUZ12
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984653
Quick Overview for SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12) Peptide (ABIN984653)
Target
SUZ12
(SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SUZ12 antibody (Catalog #: ARP39190_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))
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Background
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A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7,17)(p15,q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CHET9, JJAZ1, KIAA0160
Protein Interaction Partner: AEBP2,EED,RBBP4,AEBP2,EZH2,AEBP2,CTCF,EED,EZH2,GTF2I,JARID2,MTF2,RBBP4,SETDB1,SNAI1,UBE2I,VAV1,WDR77
Protein Size: 739 -
Molecular Weight
- 83 kDa
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Gene ID
- 23512
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NCBI Accession
- NM_015355, NP_056170
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UniProt
- Q15022
Target
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