SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide
SWAP70
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984655
Quick Overview for SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide (ABIN984655)
Target
SWAP70
(SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SWAP70 antibody (Catalog #: ARP46214_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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Background
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Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: CELSR3,IGHG1,PARP1,NCL,NPM1,PARP1
Protein Size: 585 -
Molecular Weight
- 69 kDa
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Gene ID
- 23075
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NCBI Accession
- NM_015055, NP_055870
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UniProt
- Q9UH65
Target
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