Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (C-Term) Peptide
SYNGAP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984669
Quick Overview for Synaptic Ras GTPase Activating Protein 1 (SYNGAP1) (C-Term) Peptide (ABIN984669)
Target
SYNGAP1
(Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SYNGAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))
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Background
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The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Size: 1343 -
Molecular Weight
- 148 kDa
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Gene ID
- 8831
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NCBI Accession
- NM_006772, NP_006763
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UniProt
- Q96PV0
Target
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