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TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) Peptide

TBC1D10C Reactivity: Human Host: Synthetic BP, WB

Catalog No. ABIN984786

Quick Overview for TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) Peptide (ABIN984786)

Target

Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)

Protein Region

N-Term

Characteristics

This is a synthetic peptide designed for use in combination with anti-TBC1D10C antibody (Catalog #: ARP55894_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
TBC1 Domain Family, Member 10C (TBC1D10C) peptide
TBC1D10C Reactivity: Human, Dog, Mouse, Pig, Rat Host: Synthetic BP, Imm

TBC1 Domain Family, Member 10C (TBC1D10C) peptide
TBC1D10C Host: Synthetic BP, WB, IHC

TBC1 Domain Family, Member 10C (TBC1D10C) peptide
TBC1D10C Host: Synthetic BP, WB, IHC

TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) peptide
TBC1D10C Reactivity: Human BP Sodium azide

TBC1 Domain Family, Member 10C (TBC1D10C) (C-Term) peptide
TBC1D10C Reactivity: Human BP Sodium azide

TBC1 Domain Family, Member 10C (TBC1D10C) (N-Term) peptide
TBC1D10C Reactivity: Human Host: Synthetic BP, WB

TBC1 Domain Family, Member 10C (TBC1D10C) peptide
TBC1D10C Reactivity: Human Host: Synthetic BP, BI

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

Background

TBC1D10C inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. TBC1D10C acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras.Carabin is an endogenous inhibitor of calcineurin (see MIM 114105) that also inhibits the Ras (see MIM 190020) signaling pathway through its intrinsic Ras GTPase-activating protein activity (Pan et al., 2007 [PubMed 17230191]).[supplied by OMIM].

Alias Symbols: FLJ00332, MGC46488, EPI64C, CARABIN

Protein Interaction Partner: PPP3R2

Protein Size: 446

Molecular Weight

50 kDa

Gene ID

374403

NCBI Accession

NM_198517, NP_940919

UniProt

Q8IV04

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