TBP-Like 1 (TBPL1) Peptide
TBPL1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN984812
Quick Overview for TBP-Like 1 (TBPL1) Peptide (ABIN984812)
Target
TBPL1
(TBP-Like 1 (TBPL1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TBPL1 antibody (Catalog #: ARP35751_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TBPL1 (TBP-Like 1 (TBPL1))
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Background
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Interaction Partner: ABCF3,C2orf18,GTF2A1,GTF2A2,GTF2B,IRAK4,NDUFA6,NF1,PLIN3,PTCD3,RAB35,RPL10,GTF2A1,GTF2A2,GTF2B,HSPA9,NDUFA6,PMVK,RAB35,RPL10,TAF1,TAF1L,TAF4,TAF5,TAF6,TBP,TBPL2
Protein Size: 186 -
Molecular Weight
- 21 kDa
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Gene ID
- 9519
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NCBI Accession
- NM_004865, NP_004856
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UniProt
- P62380
Target
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