Transcription Elongation Factor A (SII), 3 (TCEA3) (C-Term) Peptide
TCEA3
Reactivity: Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN984868
Quick Overview for Transcription Elongation Factor A (SII), 3 (TCEA3) (C-Term) Peptide (ABIN984868)
Target
TCEA3
(Transcription Elongation Factor A (SII), 3 (TCEA3))
Origin
Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LKDPRNPGLR RNVLSGAISP ELIAKMTAEE MASDELRELR NAMTQEAIRE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Tcea3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCEA3 (Transcription Elongation Factor A (SII), 3 (TCEA3))
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Background
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Tcea3 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
Alias Symbols: S-II, SII-K1
Protein Size: 347 -
Molecular Weight
- 39 kDa
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Gene ID
- 21401
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NCBI Accession
- NM_011542, NP_035672
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UniProt
- P23881
Target
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