Transcription Factor 4 (TCF4) Peptide
TCF4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TCF4 products
- TCF4 (Transcription Factor 4 (TCF4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF4 antibody (Catalog #: P100776_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TCF4 (Transcription Factor 4 (TCF4))
- Background
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TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well.TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well. TCF4 is known to produce multiple transcripts, however as the complete structure is only known for the transcript that encodes the b isoform, that is the variant presented here.
Alias Symbols: E2-2, ITF2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, PTHS, ITF-2, SEF-2, TCF-4, bHLHb19
Protein Interaction Partner: RUNX1T1,AR,ASCL1,CALM1,CALM3,CALM3,CDC73,EP300,HBP1,ID1,ID2,ID3,ID4,JUN,JUP,MSC,MYOD1,NEUROD1,PARP1,RUNX1T1,TCF4,XRCC5,XRCC6,AR,ASCL1,CALM1,CTNNB1,HBP1,ID1,ID2,ID3,LYL1,MSC,MYOD1,TAL1,TAL2
Protein Size: 667 - Molecular Weight
- 71 kDa
- Gene ID
- 6925
- NCBI Accession
- NM_003199, NP_003190
- UniProt
- P15884
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