Tyrosine Hydroxylase (TH) (N-Term) Peptide
TH
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985048
Quick Overview for Tyrosine Hydroxylase (TH) (N-Term) Peptide (ABIN985048)
Target
Tyrosine Hydroxylase (TH)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TH antibody (Catalog #: ARP30889_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Tyrosine Hydroxylase (TH)
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Background
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The specific function of the protein remains unknown. The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alias Symbols: TYH, DYT14, DYT5b
Protein Interaction Partner: CAMK2G,CDK11B,CSNK2A1,MAPK1,MAPK3,MAPKAPK2,PRKACA,RPS6KA5,SNCA,YWHAB,YWHAZ,HR,MAPK1,MAPK3
Protein Size: 528 -
Molecular Weight
- 58 kDa
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Gene ID
- 7054
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NCBI Accession
- NM_199292, NP_954986
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UniProt
- P07101
Target
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