Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide
TMED10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985174
Quick Overview for Transmembrane Emp24-Like Trafficking Protein 10 (TMED10) (Middle Region) Peptide (ABIN985174)
Target
TMED10
(Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TMED10 antibody (Catalog #: ARP58728_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))
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Background
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TMED10 is involved in vesicular protein trafficking.This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
Alias Symbols: P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I, p23
Protein Interaction Partner: APH1A,ARF1,NCSTN,PSENEN,TMED2,GORASP2
Protein Size: 219 -
Molecular Weight
- 24 kDa
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Gene ID
- 10972
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NCBI Accession
- NM_006827, NP_006818
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UniProt
- P49755
Target
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