Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide
TMEM173
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985225
Quick Overview for Transmembrane Protein 173 (TMEM173) (Middle Region) Peptide (ABIN985225)
Target
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TMEM173 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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Background
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This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Alias Symbols: ERIS, MITA, MPYS, SAVI, NET23, STING, hMITA, hSTING
Protein Size: 379 -
Molecular Weight
- 42 kDa
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Gene ID
- 340061
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NCBI Accession
- NM_198282, NP_938023
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UniProt
- Q86WV6
Target
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