TNF Receptor-Associated Factor 1 (TRAF1) (Middle Region) Peptide
TRAF1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985436
Quick Overview for TNF Receptor-Associated Factor 1 (TRAF1) (Middle Region) Peptide (ABIN985436)
Target
TRAF1
(TNF Receptor-Associated Factor 1 (TRAF1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRAF1 antibody (Catalog #: AVARP09008_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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TNF Receptor-Associated Factor 1 (TRAF1) peptide
TRAF1 Reactivity: Human, Mouse Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))
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Background
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This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors.The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EBI6, MGC:10353
Protein Interaction Partner: BIRC2,BIRC3,MAP3K14,TNFRSF8,TRAF2,BIRC2,BIRC3,CASP10,CASP3,CASP6,CASP8,CD40,CFLAR,EDAR,GFI1B,HIVEP3,MAP3K14,MAP6,NGFRAP1,RIPK1,RIPK2,SPOP,SRC,TANK,TICAM1,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF19,TNFRSF1A,TNFRSF1B,TNFRSF4,TNFRSF8,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAF3IP2,TRAIP,TRIM37,USP7,BIRC2,BIRC3,CASP10,CASP6,CASP8,CD27,CFLAR,HIVEP3,LTBR,MAP3K14,MAP3K5,NGFR,RIPK1,RIPK2,SPOP,SRC,TANK,TNFAIP3,TNFRSF11A,TNFRSF12A,TNFRSF14,TNFRSF17,TNFRSF18,TNFRSF1A,TNFRSF1B,TNFRSF9,TNFSF9,TRADD,TRAF2,TRAIP,TRIM37,USP7
Protein Size: 416 -
Molecular Weight
- 46 kDa
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Gene ID
- 7185
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NCBI Accession
- NM_005658, NP_005649
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UniProt
- Q13077
Target
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