Tripartite Motif Containing 23 (TRIM23) (Middle Region) Peptide
TRIM23
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985498
$160.46
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100 μg
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Quick Overview for Tripartite Motif Containing 23 (TRIM23) (Middle Region) Peptide (ABIN985498)
Target
TRIM23
(Tripartite Motif Containing 23 (TRIM23))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM23 antibody (Catalog #: ARP32672_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM23 (Tripartite Motif Containing 23 (TRIM23))
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Background
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TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Alias Symbols: ARD1, ARFD1, RNF46
Protein Interaction Partner: C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM29,TRIM31,ZNF250,ZNF581,C19orf57,CYTH1,CYTH2,FLAD1,GEM,GGA2,LNX1,POM121,RIBC2,SF1,TRIM23,TRIM27,TRIM28,TRIM29,TRIM31,TRIM32,TRIM6,ZNF250,ZNF581
Protein Size: 546 -
Molecular Weight
- 61 kDa
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Gene ID
- 373
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NCBI Accession
- NM_033228, NP_150231
Target
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