Tripartite Motif Containing 24 (TRIM24) (Middle Region) Peptide
TRIM24
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TRIM24 products
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM24 antibody (Catalog #: ARP34449_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
- Background
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The exact function of TRIM24 remains unknown. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1
Protein Interaction Partner: ESR1,AR,CBX1,CBX3,CBX5,ESR1,ESR2,GTF2E1,HNF4A,HSPA1A,NR2F2,NR3C1,NR3C2,PGR,PML,RARA,RXRA,SUMO1,TAF11,TAF1B,TAF1C,TAF7,THRA,TRIM24,TRIM28,TRIM33,VDR,ZNF10,AR,ESR1,GTF2E1,NR3C1,NR3C2,PML,RARA,RXRA,TAF11,TAF7,THRA,TRIM24,TRIM28,TRIM33,ZNF10
Protein Size: 1050 - Molecular Weight
- 117 kDa
- Gene ID
- 8805
- NCBI Accession
- NM_015905, NP_056989
- UniProt
- O15164
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