Tripartite Motif Containing 25 (TRIM25) (Middle Region) Peptide
TRIM25
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN985502
Quick Overview for Tripartite Motif Containing 25 (TRIM25) (Middle Region) Peptide (ABIN985502)
Target
TRIM25
(Tripartite Motif Containing 25 (TRIM25))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- LLDASETTST RKIKEEEKRV NSKFDTIYQI LLKKKSEIQT LKEEIEQSLT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRIM25 Antibody(ARP58105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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Background
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Alias Symbols: EFP, RNF147, Z147, ZNF147
Protein Interaction Partner: SFN,TFG,TRIM25,UBE2L6,DDX58,ERCC2,ESR1,GATA1,ISG15,MEIS2,PITX2,RARRES3,SFN,STK38,TRIM25,UBC,UBE2D1,UBE2D2,UBE2D3,UBE2D4,UBE2J2,UBE2L6,UBE2N,ZNF24
Protein Size: 630 -
Molecular Weight
- 71 kDa
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Gene ID
- 7706
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NCBI Accession
- NM_005082, NP_005073
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UniProt
- Q14258
Target
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