Translin (TSN) (Middle Region) Peptide
Quick Overview for Translin (TSN) (Middle Region) Peptide (ABIN985673)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- LVTREAVTEI LGIEPDREKG FHLDVEDYLS GVLILASELS RLSVNSVTAG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TSN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Translin (TSN)
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Background
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This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Alias Symbols: BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN
Protein Interaction Partner: HCVgp1,TSNAX,PPP1R15A,TSNAX,PPP1R15A,TSNAX
Protein Size: 228 -
Molecular Weight
- 25 kDa
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Gene ID
- 7247
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NCBI Accession
- NM_004622, NP_004613
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UniProt
- Q15631
Target
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