tyrosyl-DNA phosphodiesterase 2 (TDP2) Peptide
TDP2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN985724
Quick Overview for tyrosyl-DNA phosphodiesterase 2 (TDP2) Peptide (ABIN985724)
Target
TDP2
(tyrosyl-DNA phosphodiesterase 2 (TDP2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TTRAP antibody (Catalog #: ARP33010_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))
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Background
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The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Alias Symbols: TDP2, EAP2, AD022, EAPII, TTRAP, dJ30M3.3, RP1-30M3.3
Protein Interaction Partner: ETS1,ETS1,ETS2,FLI1,HTNVsSgp1,SUMO1,UBE2I,CD40,ETS1,ETS2,FLI1,SKIL,SUMO1,TNFRSF1B,TNFRSF8,TRAF2,TRAF3,TRAF5,TRAF6,UBE2I,CD40,ETS1,SUMO1,TNFRSF1B,TNFRSF8,TRAF2,TRAF3,TRAF5,TRAF6,UBE2I
Protein Size: 362 -
Molecular Weight
- 41 kDa
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Gene ID
- 51567
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NCBI Accession
- NM_016614, NP_057698
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UniProt
- O95551
Target
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