Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) (N-Term) Peptide
NPRL2
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN985758
Quick Overview for Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2) (N-Term) Peptide (ABIN985758)
Target
NPRL2
(Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-TUSC4 antibody (Catalog #: ARP50539_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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Background
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TUSC4 suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. TUSC4 down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. TUSC4 may act as a tumor suppressor. TUSC4 suppresses cell growth and enhanced sensitivity to various anticancer drugs.
Alias Symbols: NPR2L, NPRL2, NPR2, TUSC4
Protein Interaction Partner: NPRL3,PRKAR1A,UBE2M
Protein Size: 380 -
Molecular Weight
- 44 kDa
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Gene ID
- 10641
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NCBI Accession
- NM_006545, NP_006536
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UniProt
- Q8WTW4
Target
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