Vanin 2 (VNN2) (C-Term) Peptide
VNN2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all VNN2 products
- VNN2 (Vanin 2 (VNN2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FRGFISRDGF NFTELFENAG NLTVCQKELC CHLSYRMLQK EENEVYVLGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-VNN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- VNN2 (Vanin 2 (VNN2))
- Background
-
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FOAP-4, GPI-80
Protein Interaction Partner: ITGB2,ITGB2
Protein Size: 520 - Molecular Weight
- 57 kDa
- Gene ID
- 8875
- NCBI Accession
- NM_004665, NP_004656
- UniProt
- O95498
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