WAP Four-Disulfide Core Domain 1 (WFDC1) (N-Term) Peptide
WFDC1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN986193
Quick Overview for WAP Four-Disulfide Core Domain 1 (WFDC1) (N-Term) Peptide (ABIN986193)
Target
WFDC1
(WAP Four-Disulfide Core Domain 1 (WFDC1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- WKRALPARLA EKSRAEEAGA PGGPRQPRAD RCPPPPRTLP PGACQAARCQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-WFDC1 Antibody(ARP57525_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
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Background
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This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.
Alias Symbols: PS20
Protein Size: 220 -
Molecular Weight
- 21 kDa
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Gene ID
- 58189
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NCBI Accession
- NM_021197, NP_067020
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UniProt
- Q9HC57
Target
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