Exportin 1 (XPO1) Peptide
XPO1
Reactivity: Human
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN986259
Quick Overview for Exportin 1 (XPO1) Peptide (ABIN986259)
Target
XPO1
(Exportin 1 (XPO1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-XPO1 antibody (Catalog #: ARP40465_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- XPO1 (Exportin 1 (XPO1))
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Background
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XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRM1, DKFZp686B1823, emb, exp1
Protein Interaction Partner: CDKN1B,DDX3X,NPM1,NUPL2,SNORD3A,ADAR,AGFG1,AHR,ATF2,BECN1,BIRC5,CDKN1B,CIITA,CRK,DDX3X,E2F5,EIF5A,ERF,FOXO4,HDAC3,IRF5,KIF17,MAPK6,NF2,NMD3,NPM1,NUP153,NUP214,NUP50,NUP62,NXF3,NXT1,ORC1L,PHAX,PHB,RAN,RANBP2,RANBP3,RCC1,RPS6KB1,SMAD1,SMARCB1,SMURF1,SNUPN,STAT1,TERT,TOP2A,TOP2B,XPO1,ADAR,AIRE,APC,ARNT,CCND1,CDKN1B,CIITA,CRK,EIF5A,FOXO4,HDAC3,MEPCE,NMD3,NUP153,NUP214,NUP62,NXF3,NXT1,PMS2,RAN,RANBP1,RANBP3,RCC1,RPS6KB1,SMARCB1,SNUPN
Protein Size: 1071 -
Molecular Weight
- 123 kDa
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Gene ID
- 7514
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NCBI Accession
- NM_003400, NP_003391
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UniProt
- O14980
Target
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