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PITM1 Protein (AA 1-238, partial) (GST tag)

This Recombinant PITM1 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN5712199

Quick Overview for PITM1 Protein (AA 1-238, partial) (GST tag) (ABIN5712199)

Target

PITM1 (Prion Incubation Time 1 (PITM1))

Protein Type

Recombinant

Origin

Human

Source

Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 90 %
  • Protein Characteristics

    AA 1-238, partial

    Purification tag / Conjugate

    This PITM1 protein is labelled with GST tag.

    Sequence

    MLIKEYHILL PMSLDEYQVA QLYMIQKKSR EESSGEGSGV EILANRPYTD GPGGSGQYTH KVYHVGSHIP GWFRALLPKA ALQVEEESWN AYPYTRTRYT CPFVEKFSIE IETYYLPDGG QQPNVFNLSG AERRQRILDT IDIVRDAVAP GEYKAEEDPR LYHSVKTGRG PLSDDWARTA AQTGPLMCAY KLCKVEFRYW GMQAKIEQFI HDVGLRRVML RAHRQAWCWQ DEWTELSM

    Purification

    SDS-PAGE
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.1-2 mg/mL

    Buffer

    20 mM Tris-HCl based buffer, pH 8.0

    Storage

    -80 °C,4 °C,-20 °C

    Storage Comment

    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target

    PITM1 (Prion Incubation Time 1 (PITM1))

    Alternative Name

    PITM1

    Background

    Regulates RHOA activity, and plays a role in cytoskeleton rodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between mbranes . Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.4 Publications

    Molecular Weight

    54.9 kDa

    UniProt

    O00562
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