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anti-Human Cyclin D1 Antibodies:
anti-Mouse (Murine) Cyclin D1 Antibodies:
anti-Rat (Rattus) Cyclin D1 Antibodies:
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Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN5518654
Li, Xu, Chu, Gao, Wang, Nie, Yang, Lv: Molecular mechanism of inhibitory effects of CD59 gene on atherosclerosis in ApoE (-/-) mice. in Immunology letters 2013
Show all 40 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN3044355
Ren, Huang, Xu, Yang, Yang, Hu: Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. in Anti-cancer drugs 2015
Show all 36 Pubmed References
Human Monoclonal Cyclin D1 Primary Antibody for ICC, IHC (fro) - ABIN3043639
Li, Zhu, Liu, Liu, Wang, Xiong, Shen, Hu, Zheng: ZFX knockdown inhibits growth and migration of non-small cell lung carcinoma cell line H1299. in International journal of clinical and experimental pathology 2013
Show all 36 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN3043483
Wu, Tao, Chen, Xu: RhoC regulates the proliferation of gastric cancer cells through interaction with IQGAP1. in PLoS ONE 2012
Show all 21 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for ELISA, ICC - ABIN6261145
Ge, Wang, Ruan, Chen, Liu, Ye: Overexpression of p53 activated by small activating RNA suppresses the growth of human prostate cancer cells. in OncoTargets and therapy 2016
Show all 10 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN1881175
Aggarwal, Vaites, Kim, Mellert, Gurung, Nakagawa, Herlyn, Hua, Rustgi, McMahon, Diehl: Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. in Cancer cell 2010
Show all 6 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for CyTOF, FACS - ABIN4899040
MacLeod et al.: Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/β-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced ... in Laboratory investigation; a journal of technical methods and pathology 2013
Show all 5 Pubmed References
Human Monoclonal Cyclin D1 Primary Antibody for ELISA, WB - ABIN969007
Parafioriti, del Bianco, Barisani, Armiraglio, Peretti, Albisetti: Increased p21 expression in chondrocytes of achondroplasic children independently from the presence of the G380R FGFR3 mutation. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2009
Show all 2 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for WB - ABIN389145
He, Council, Feng, Chignell: UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytes. in Cancer research 2008
Show all 5 Pubmed References
Human Polyclonal Cyclin D1 Primary Antibody for IHC (p), WB - ABIN4301538
Ray, Vasudevan, Sengupta: 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death. in PLoS ONE 2015
Show all 2 Pubmed References
High CCND1 expression is associated with lung adenocarcinoma.
Down-regulation of Apaf-1 (show APAF1 Antibodies) protein and the overexpression of Cyclin D1 and AQP-5 (show AQP5 Antibodies) proteins possibly contribute to an aggressive serous ovarian carcinoma with a high risk of recurrence and poor response to the first-line chemotherapy.
Results provide evidence that Cyclin D1 is a mediator for WDR5 (show WDR5 Antibodies)-induced proliferation and cell cycle change in gastric neoplasm.
CNV analysis disclosed that plasma CCND1/CDKN2A ratio is correlated with EBV DNA load in NPC (show NPC1 Antibodies) patients' plasma and could serve as a screening test to select potential CDK4/6 (show CDK4 Antibodies) inhibitor treatment candidates. Based on our NPC (show NPC1 Antibodies) PDX model and RNA sequencing, Palbociclib, a cyclin-dependent kinase (show CDK1 Antibodies) inhibitor, proved to have anti-tumor effects by inducing G1 arrest.
Cyclin (show PCNA Antibodies) D1b markedly amplified integrin alphavbeta3 (show ITGAV Antibodies) expression, which was further up-regulated under lipopolysaccharide stimulation.
This meta-analysis suggested that CCND1 rs9344 polymorphism might be associated with the risk of HCC (show FAM126A Antibodies) among Caucasians.
Results show that CCND1 expression is regulated by LET7A which directly targets its 3'UTR (show UTS2R Antibodies) in A549 lung cancer cells.
Authors found that the phenotypic alterations by miR (show MLXIP Antibodies)-365 were partially due to downregulation of CCND1 and BCL2 (show BCL2 Antibodies) oncogenes.
USP22 (show USP22 Antibodies) and CCND1 levels correlate in patient lung and colorectal cancer samples and our preclinical studies indicate that targeting USP22 (show USP22 Antibodies) in combination with CDK (show CDK4 Antibodies) inhibitors may offer an approach for treating cancer patients whose tumors exhibit elevated CCND1.
miR449a5p may control squamous cell carcinoma proliferation through the negative regulation of cyclin D1 expression.
results suggest that DGKdelta controls the down-regulation of cyclin D1 expression by attenuating the PKC signaling pathway for C2C12 myogenic differentiation
the focal adhesion component paxillin (show PXN Antibodies) is a cytoplasmic substrate of Ccnd1.Cdk4 (show CDK4 Antibodies).
Since miR (show MLXIP Antibodies)-290 cluster miRNAs are the most dominant stem-cell-specific miRNAs, our results revealed an important cause for the absence of Cyclin D1 in mouse embryonic stem cells
beta-catenin (show CTNNB1 Antibodies) and p65 (show NFkBP65 Antibodies) are activated in separate cellular compartments during liver regeneration, with p65 (show NFkBP65 Antibodies) activity in nonparenchymal compartment contributing to the activation of hepatocyte beta-catenin (show CTNNB1 Antibodies), cyclin D1 expression, and subsequent proliferation
Ablation of periostin (show POSTN Antibodies) suppresses post-infarction myocardial regeneration by inhibiting the PI3K/GSK3beta/cyclin D1 signalling pathway, indicating that periostin (show POSTN Antibodies) is essential for myocardial regeneration.
Cyclin D1 is indispensable for normal hematopoiesis; in its absence, cyclins D2 and D3 are also not expressed, preventing hematopoietic cell division and differentiation at its earliest stage. The results demonstrate that not all functions of individual D cyclins are redundant, and highlight a master role of cyclin D1 in hematopoiesis.
NMB or NMBR (show NMBR Antibodies) silencing inhibited M-CSF (show CSF1R Antibodies)/c-Fms (show CSF1R Antibodies)-mediated downstream signaling pathways like activation of ERK (show EPHB2 Antibodies) and Akt (show AKT1 Antibodies) and induction of D-type cyclins, cyclin D1 and D2.
Histone H2A T120 phosphorylation promotes oncogenic transformation via upregulation of cyclin D1.
our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1 (show CTNNB1 Antibodies)-driven Ccnd1 transcription and estrogen-mediated CCND1 protein stabilization.
identify Pax5 (show PAX5 Antibodies) and cyclin D1 as Zfp521 (show ZNF521 Antibodies) target genes, and suggest that excessive B-cell proliferation observed in mice with retroviral insertions near the Zfp521 (show ZNF521 Antibodies) gene is due to an up-regulation of cyclin D1 in B-cells.
Methylparabens exposure increased malformations, LPO, apoptosis, ccnd1 and myca expressions, and decreased GST activities and NO levels compared with the control group.
while cyclin B1 RNA granules were disassembled in a manner dependent on actin filament depolymerization, certain fractions of mos RNA granules were disassembled independently of actin filaments. These results suggest that cytoplasmic regulation of translationally repressed mRNAs by formation of different RNA granules is a key mechanism for translational control of
show that the knockdown of smc1a (show SMC1A Antibodies) in zebrafish impairs neural development, increases apoptosis, and specifically down-regulates Ccnd1 levels
Reduction of cyclin D1 expression compromises zebrafish eye and head development.
Role in cell cycle control is mediated by meis1 (show MEIS1 Antibodies) regulating cyclin D1 and c-myc (show MYC Antibodies) transcription in the embryonic eye.
Results suggest that the TCF (show HNF4A Antibodies)/LEF signaling pathway participates in the regulation of cyclin D1 induction during the generation of the dorsal nervous system in early frog embryogenesis.
CCND1 mRNA expression is increased by FGF9 in bovine theca cells and granulosa cells.
cyclin D1, CDK2 (show CDK2 Antibodies) and CDK4 (show CDK4 Antibodies) are expressed in both caruncular and intercaruncular cells derived from both nonpregnant, and artificially inseminated cows on days 30 and 60 of gestation
17beta-estradiol (E2) induces cell proliferation of bovine arterial endothelial cells through upregulation of cyclin D1 via non-genomic activation of the extracellular signal-regulated microtubule-associated Protein 2 kinase (ERK1 (show MAPK3 Antibodies) kinase) pathway.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
B-cell CLL/lymphoma 1
, B-cell lymphoma 1 protein
, BCL-1 oncogene
, G1/S-specific cyclin-D1
, PRAD1 oncogene
, G1/S-specific cyclin-D1 b
, cyclin D1 b
, parathyroid adenomatosis 1
, G1/S-specific cyclin-D1 a
, cyclin D1 a (PRAD1: parathyroid adenomatosis 1)
, cyclin D1 (PRAD1: parathyroid adenomatosis 1)
, cyclin D1