Cyclin D1 Products
(Cyclin D1 (CCND1))
Categories
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008].
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Featured Cyclin D1 Categories
Cyclin D1 Antibodies
High quality antibodies with extensive validation data.
Cyclin D1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cyclin D1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cyclin D1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Human, Mouse, Rabbit, Rat, Sheep
Application
WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p)
Validations
- (15)
- (6)
Cat. No.
ABIN671016
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN389146
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (6)
Cat. No.
ABIN5542302
Quantity
0.1 mg
Datasheet
Datasheet
Recommended Cyclin D1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (8)
- (1)
Cat. No.
ABIN6955147
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6955148
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966156
Quantity
96 tests
Datasheet
Datasheet
Recommended Cyclin D1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1348445
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122523
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3091313
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Cyclin D1 products
: "LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer." in: Cancer medicine, Vol. 9, Issue 2, pp. 724-736, (2021) (PubMed).: "The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 327, (2021) (PubMed).
: "ASIC1a Inhibitor mambalgin-2 Suppresses the Growth of Leukemia Cells by Cell Cycle Arrest." in: Acta naturae, Vol. 12, Issue 2, pp. 101-116, (2020) (PubMed).
: "Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways." in: Stem cell research & therapy, Vol. 10, Issue 1, pp. 47, (2020) (PubMed).
: "Development of a dietary formulation of the SHetA2 chemoprevention drug for mice." in: Investigational new drugs, Vol. 36, Issue 4, pp. 561-570, (2019) (PubMed).
: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).
: "DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia." in: Nature communications, Vol. 10, Issue 1, pp. 2278, (2019) (PubMed).
: "Synthesis of novel S-linked dihydroartemisinin derivatives and evaluation of their anticancer activity." in: European journal of medicinal chemistry, Vol. 178, pp. 552-570, (2019) (PubMed).
: "Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase inhibitors." in: Biochemical pharmacology, Vol. 152, pp. 327-337, (2019) (PubMed).
: "Is there an association between enhanced choline and β-catenin pathway in breast cancer? A pilot study by MR Spectroscopy and ELISA." in: Scientific reports, Vol. 7, Issue 1, pp. 2221, (2018) (PubMed).
Synonyms and alternative names related to Cyclin D1
cyclin D1 (CCND1), cyclin D1 (Ccnd1), cyclin D1 (ccnd1), cyclin D1 S homeolog (ccnd1.S), cyclin D1 L homeolog (ccnd1.L), AI327039, bcl-1, BCL1, bcl1, cb161, ccnd1, CCND1, ccnd1a, ccnd1b, cD1, CycD1, cycd1, Cyl-1, D11S287E, d11s287e, etID37810.7, fb52e01, fc45c08, fc83a12, id:ibd1198, PRAD1, prad1, U21B31, u21b31, wu:fb52e01, wu:fc45c08, wu:fc83a12Protein level used designations for Cyclin D1
- B-cell CLL/lymphoma 1
- B-cell lymphoma 1 protein
- BCL-1 oncogene
- G1/S-specific cyclin-D1
- PRAD1 oncogene
- G1/S-specific cyclin-D1 b
- cyclin D1 b
- parathyroid adenomatosis 1
- G1/S-specific cyclin-D1 a
- cyclin D1 a (PRAD1: parathyroid adenomatosis 1)
- cyclin D1 (PRAD1: parathyroid adenomatosis 1)
- cyclin D1
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