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anti-Human ARID5B Antibodies:
anti-Mouse (Murine) ARID5B Antibodies:
anti-Cow (Bovine) ARID5B Antibodies:
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Human Polyclonal ARID5B Primary Antibody for ICC, IF - ABIN4281577
Hata, Takashima, Amano, Ono, Nakanishi, Yoshida, Wakabayashi, Matsuda, Maeda, Suzuki, Sugano, Whitson, Nishimura, Yoneda: Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes. in Nature communications 2013
Show all 2 Pubmed References
Cow (Bovine) Polyclonal ARID5B Primary Antibody for WB - ABIN610895
Aspberg, Miura, Bourdoulous, Shimonaka, Heinegârd, Schachner, Ruoslahti, Yamaguchi: The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety. in Proceedings of the National Academy of Sciences of the United States of America 1997
arid5b isoform1 and isoform2 are differentially expressed during development. Isoform1 is strongly expressed maternally, while isoform2 expression is essentially restricted to tailbud stages. arid5b is predominantly expressed in the developing pronephros.
Differential methylation and expression of ARID5B to be associated with human atherosclerosis.
The present results identified MRF2/ARID5B as a potential susceptibility gene for new-onset T2DM in a Northern Chinese population, while the rs7087507 SNP was associated with HDL (show HSD11B1 Antibodies)-C levels. Further larger studies are required to validate these findings.
We systematically screened 6 potentially functional SNPs in ARID5B and IKZF1 genes.
ARID5B reinforces the oncogenic transcriptional program by positively regulating the TAL1 (show TAL1 Antibodies)-induced regulatory circuit and MYC (show MYC Antibodies) in T-ALL, thereby contributing to T-cell leukemogenesis.
Results identified a novel hotspot in the terminal exon of ARID5B.The ARID5B indel mutations were seen in both mismatch repair (MMR (show MRC1 Antibodies))-deficient and MMR (show MRC1 Antibodies)-normal tumors, suggesting biologic selection in endometrial neoplasm.
Our results confirmed the role of ARID5B in childhood ALL susceptibility among Hispanics; however, our assessment did not reveal any strong novel inherited genetic risks for acute lymphoblastic leukemia among this ethnic group.
Associations between ALL and rs10821936 and rs7089424 ARID5B SNPs were found
ARID5B variants are associated with acute lymphoblastic leukemia in Yemeni children with several gender biases of ARID5B single nucleotide polymorphisms reported.
variants within IKZF1 (show IKZF1 Antibodies), ARID5B, and CEBPE (show CEBPE Antibodies) were associated with pediatric ALL risks.
Genotypic and allelic frequencies differed significantly between cases and controls at IKZF1 (show IKZF1 Antibodies)-rs4132601 (p=0.039, p=0.015) and ARID5B-rs10821936 (p=0.028, p=0.026).
These results strongly suggest that p62 plays a crucial role in preventing fenofibrate-induced cell death.
Arid5b recruits Phf2 (show PHF2 Antibodies) to the promoter region of Sox9 (show SOX9 Antibodies) target genes and stimulates H3K9me2 demethylation of these genes.
knockdown of Mrf-2 increases the rate of fatty acid recycling in 3T3-L1-derived adipocytes.
phenotypes suggest that Mrf-2 is essential for accumulation of lipid stores in postnatal life
Data suggest that Mrf-2 facilitates the induction of key adipogenic transcription factors C/EBPalpha (show CEBPA Antibodies) and peroxisome proliferator-activated receptor-gamma (show PPARG Antibodies).
These results indicate that Mrf2 can be a potential regulator of adipocyte differentiation and a potential repressor of leptin (show LEP Antibodies).
This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
AT rich interactive domain 5B (MRF1-like)
, AT-rich interactive domain-containing protein 5B
, AT-rich interactive domain-containing protein 5B-like
, ARID domain-containing protein 5B
, MRF1-like protein
, modulator recognition factor 2 (MRF2)
, ARID class DNA binding protein
, AT rich interactive domain 5B (Mrf1 like)
, developmentally and sexually retarded with transient immune abnormalities protein
, modulator recognition factor 2
, modulator recognition factor protein 2