ARID5B antibody (C-Term)

Catalog No. ABIN2784295

This Rabbit Polyclonal antibody specifically detects ARID5B in WB. It exhibits reactivity toward Human, Cow, Horse, Rabbit, Rat, Guinea Pig and Mouse.

Quick Overview for ARID5B antibody (C-Term) (ABIN2784295)

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Reactivity: Human, Cow, Horse, Rabbit, Rat, Guinea Pig, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID5B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARID5B Antibody

Binding Specificity: C-Term

Purpose: ARID5B Antibody - C-terminal region

Sequence: VSPLDPSKEV SGKEKASEQE SEGSKAAHGG HSGGGSEGHK LPLSSPIFPG

Predicted Reactivity: Cow: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ARID5B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARID5B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP50705-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARID5B

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Alternative Name: ARID5B

Background:

Background Information: ARID5B is a DNA-binding protein that binds to the 5'-AATA[CT]-3' core sequence. ARID5B probably acts as a transcription regulator. ARID5B represses the cytomegalovirus enhancer. Overexpression of ARID5B leads to induction of smooth muscle marker genes, suggesting that it may act as a regulator of smooth muscle cell differentiation and proliferation. ARID5B may be involved in lipid stores.

Gene Name: AT rich interactive domain 5B (MRF1-like)

Alternative Symbols: MRF2, DESRT, MRF-2

Protein Name: AT-rich interactive domain-containing protein 5B

Molecular Weight: 132kDa

Gene ID: 84159

NCBI Accession: NP_115575

UniProt: Q14865

Pathways: Platelet-derived growth Factor Receptor Signaling