ARID5B antibody (N-Term)

Catalog No. ABIN2784294

The Rabbit Polyclonal anti-ARID5B antibody (ABIN2784294) specifically detects ARID5B in WB. The antibody is reactive with Human, Cow, Horse, Rabbit, Rat, Guinea Pig, Mouse and Dog samples.

Quick Overview for ARID5B antibody (N-Term) (ABIN2784294)

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Reactivity: Human, Cow, Horse, Rabbit, Rat, Guinea Pig, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARID5B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARID5B Antibody

Binding Specificity: N-Term

Sequence: FLPEDTPQGR NSDHGEDEVI AVSEKVIVKL EDLVKWVHSD FSKWRCGFHA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARID5B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARID5B

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARID5B

Target: ARID5B (AT Rich Interactive Domain 5B (MRF1-Like) (ARID5B))

Alternative Name: ARID5B

Background: This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: DESRT, MRF-2, MRF2
Protein Interaction Partner: UBC, SOX2, HDAC2, HDAC1, SUMO1, CAND1, ISG15, ELAVL1, SUMO2,
Protein Size: 318

Molecular Weight: 34 kDa

Gene ID: 84159

NCBI Accession: NM_032199, NP_115575

Pathways: Platelet-derived growth Factor Receptor Signaling