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anti-Human PHPT1 Antibodies:
anti-Mouse (Murine) PHPT1 Antibodies:
anti-Rat (Rattus) PHPT1 Antibodies:
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Human Polyclonal PHPT1 Primary Antibody for ICC, IF - ABIN4345386
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
PHPT1 was expressed in the epithelium of proximal tubuli and nuclei of clear-cell renal cell carcinoma (show MOK Antibodies) tissue samples.
PHPT1 can dephosphorylate phospholysine in chemically phosphorylated histone H1 (show H1F0 Antibodies) and polylysine
The specific degradation of the PHPT1 splice variant indicates that the quality control and the self-guarding of the cellular system works at two levels, first at the RNA level and proteasome level.
the histidine phosphatase, protein histidine phosphatase 1, inhibits NDPK-B-activated TRPV5 (show TRPV5 Antibodies) in inside/out patch experiments.
Overexpression of PHP (show ASAH1 Antibodies) by the use of a plasmid vector, pIRES2-AcGFP1-PHP (show ASAH1 Antibodies), induced apoptosis in HUVEC
Significantly higher expression levels of PHPT1 protein were found in lung cancer samples than in normal tissues adjacent to lung cancer.
these data implicate regulatory roles for PHPT1 in a G protein-sensitive step involved in nutrient-induced insulin (show INS Antibodies) secretion
These results demonstrate for the first time that PHP14 may be functionally important in lung cancer cell migration and the invasion of lung cancer cells, mediated partly through modulation of actin cytoskeleton rearrangement.
Overexpression of PHP (show ASAH1 Antibodies) results in increased dephosphorylation with concomitant inactivation of ACL (show ACLY Antibodies), thus finally leading to cell damage.
PHPT-1 functions to negatively regulate CD4 (show CD4 Antibodies) T cells
PHPT-1(-/-) mice exhibited neonatal hyperinsulinemic hypoglycemia due to impaired trafficking of KATP channels to the plasma membrane in pancreatic beta-cells in response to low glucose and leptin (show LEP Antibodies) and resembled patients with congenital hyperinsulinism (CHI).
PHPT1 is an EDTA-insensitive phosphohistidine phosphatase that catalyzes the dephosphorylation of phosphopeptide I (Ek et al., 2002
phosphohistidine phosphatase 1
, 14 kDa phosphohistidine phosphatase
, phosphohistidine phosphatase 14kDa
, protein janus-A homolog
, sex-regulated protein janus-a
, 14kDa phosphohistidine phosphatase