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Human Polyclonal SKIL Primary Antibody for IHC, ELISA - ABIN1003171
Li, Turck, Teumer, Stavnezer: Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene. in Journal of virology 1986
Show all 4 Pubmed References
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
, Ski-like protein
, ski-like protein-like
, ski-like protein
, ski-related oncogene
, ski/sno related
, ski-related oncogene snoN
, v-ski sarcoma viral oncogene homolog