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SKIL Products

(SKI-Like Oncogene (SKIL))

Categories

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Featured SKIL Categories

SKIL Antibodies

High quality antibodies with extensive validation data.

SKIL ELISA Kits

Reliable ELISA kits for a wide range of species.

SKIL Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SKIL Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN7169773
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, WB
Validations
  • (3)
Cat. No. ABIN6258322
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, IHC, WB
Validations
  • (3)
Cat. No. ABIN6656781
Quantity 100 μg
Datasheet Datasheet

Recommended SKIL ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959501
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6221322
Quantity 96 tests
Datasheet Datasheet

Recommended SKIL Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3077042
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3122704
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320081
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our SKIL products

Tecalco-Cruz, Sosa-Garrocho, Vázquez-Victorio, Ortiz-García, Domínguez-Hüttinger, Macías-Silva: "Transforming growth factor-β/SMAD Target gene SKIL is negatively regulated by the transcriptional cofactor complex SNON-SMAD4." in: The Journal of biological chemistry, Vol. 287, Issue 32, pp. 26764-76, (2012) (PubMed).

Luo: "Ski and SnoN: negative regulators of TGF-beta signaling." in: Current opinion in genetics & development, Vol. 14, Issue 1, pp. 65-70, (2004) (PubMed).

Derynck, Akhurst, Balmain: "TGF-beta signaling in tumor suppression and cancer progression." in: Nature genetics, Vol. 29, Issue 2, pp. 117-29, (2001) (PubMed).

Massagué, Wotton: "Transcriptional control by the TGF-beta/Smad signaling system." in: The EMBO journal, Vol. 19, Issue 8, pp. 1745-54, (2000) (PubMed).

Li, Turck, Teumer, Stavnezer: "Unique sequence, ski, in Sloan-Kettering avian retroviruses with properties of a new cell-derived oncogene." in: Journal of virology, Vol. 57, Issue 3, pp. 1065-72, (1986) (PubMed).

Synonyms and alternative names related to SKIL

SKI like proto-oncogene (SKIL), SKI-like proto-oncogene (Skil), ski-like protein (LOC100010058), SKI-like proto-oncogene (skil), SKI like proto-oncogene (skil), SKI-like (Skil), SKI like proto-oncogene (Skil), SKI-like proto-oncogene b (skilb), DKFZp459L122, SKIL, Skir, SNO, Sno, sno, SnoA, SnoI, SnoN, zgc:193698

Protein level used designations for SKIL

  • ski-like protein
  • ski-related oncogene snoN
  • ski/sno related
  • SKI-like oncogene
  • v-ski sarcoma viral oncogene homolog
  • Ski-like protein
  • ski-like protein-like
  • ski-related oncogene
  • LOW QUALITY PROTEIN: ski-like protein
  • SKI-like oncogene b
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