Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2) (AA 23-206) protein (His tag)

Catalog No. ABIN1001168

This Recombinant protein is produced in Escherichia coli (E. coli).

Quick Overview for Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2) (AA 23-206) protein (His tag) (ABIN1001168)

Target: Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: Western Blotting (WB), Control (Ct)

Purity: > 95 %

Product Details

Protein Characteristics: AA 23-206

Purification tag / Conjugate: His tag

Purpose: Soluble Tumour Necrosis Factor Receptor 2 (STNF-R2) (Western Blot Control)

Sequence: LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH LPAQVAFTPY APEPGSTCRL REYYDQTAQM CCSKCSPGQH QICNVVAIPG NASMDAVCTS TSPT

Characteristics: recombinant sTNFR-II comprises a 184 amino acid fragment (23-206) corresponding to the mature sTNFR-II protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C

Target Details

Target: Soluble Tumor Necrosis Factor Receptor Type 2 (sTNF-R2)

Background: Two types of soluble TNF receptors (sTNFR-I and sTNFRII) have been identified, which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women.,Tumour necrosis factor receptor 2, Tumour receptor beta receptor, Tumour necrosis factor binding protein 2, Tumour necrosis factor receptor superfamily member 1B, Tumour necrosis factor receptor type II, p80 TNF alpha receptor, Etanercept, CD120b, p75, TBPII, TNFRII, TNFR75, TNFBR, TNFR2, TNFR80.

Molecular Weight: 24.45 kDa

UniProt: P20333