BCL2L2 Protein (AA 2-172) (His tag)

Catalog No. ABIN1096092

This Recombinant BCL2L2 protein is produced in Escherichia coli (E. coli).

Quick Overview for BCL2L2 Protein (AA 2-172) (His tag) (ABIN1096092)

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 2-172

Purification tag / Conjugate: This BCL2L2 protein is labelled with His tag.

Purpose: Recombinant Human Bcl-2-Llike Protein 2/BCL2L2 (C-6His)

Sequence: ATPASAPDTR ALVADFVGYK LRQKGYVCGA GPGEGPAADP LHQAMRAAGD EFETRFRRTF SDLAAQLHVT PGSAQQRFTQ VSDELFQGGP NWGRLVAFFV FGAALCAESV NKEMEPLVGQ VQEWMVAYLE TRLADWIHSS GGWAEFTALY GDGALEEARR LREGNWASVR TLEHHHHHH

Characteristics: Recombinant Human Bcl-2-Llike Protein 2/BCL2L2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Thr172) of Human BCL2L2.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 25 mM HEPES, 100 mM KCl, 20 % Glycerol, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: Bcl-2-Llike Protein 2/BCL2L2

Background: Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in the brain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Alternative Names: Bcl-2-Like Protein 2, Bcl2-L-2, Apoptosis Regulator Bcl-W, BCL2L2, BCLW, KIAA0271

Molecular Weight: 19.87 kDa

UniProt: Q92843