GGCT Protein (AA 1-188) (His tag)
Quick Overview for GGCT Protein (AA 1-188) (His tag) (ABIN1096437)
Target
See all GGCT ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-188
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Purification tag / Conjugate
- This GGCT protein is labelled with His tag.
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Purpose
- Recombinant Human γ-Glutamylcyclotransferase/GGCT (N-6His)
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Sequence
- MGSSHHHHHH SSGLVPRGSH MANSGCKDVT GPDEESFLYF AYGSNLLTER IHLRNPSAAF FCVARLQDFK LDFGNSQGKT SQTWHGGIAT IFQSPGDEVW GVVWKMNKSN LNSLDEQEGV KSGMYVVIEV KVATQEGKEI TCRSYLMTNY ESAPPSPQYK KIICMGAKEN GLPLEYQEKL KAIEPNDYTG KVSEEIEDII KKGETQTL
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Characteristics
- Recombinant Human gamma-Glutamylcyclotransferase/GGCT is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu188) of Human GGCT fused with a His tag at the N-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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gamma-Glutamylcyclotransferase (GGCT) (AA 1-188) protein (His tag)
custom-made GGCT Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
gamma-Glutamylcyclotransferase (GGCT) (AA 1-188) protein (His tag)custom-made GGCT Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
gamma-Glutamylcyclotransferase (GGCT) (AA 1-188), (full length) protein (His-SUMO Tag)GGCT Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
gamma-Glutamylcyclotransferase (GGCT) protein (Myc-DYKDDDDK Tag)GGCT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
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Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Storage
- -80 °C
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Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Expiry Date
- 6 months
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- GGCT (gamma-Glutamylcyclotransferase (GGCT))
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Alternative Name
- CRF21
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Sub Type
- Fusionprotein
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Background
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Human Ypsilon-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Alternative Names: Gamma-Glutamylcyclotransferase, Cytochrome C-Releasing Factor 21, GGCT, C7orf24, CRF21 -
Molecular Weight
- 23.17kDa
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UniProt
- O75223
Target
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