ESAT6 protein (His tag)

Catalog No. ABIN1098245

This Recombinant protein is produced in Hi-5 Cells.

Quick Overview for ESAT6 protein (His tag) (ABIN1098245)

Target: ESAT6

Protein Type: Recombinant

Origin: Mycobacterium tuberculosis

Source: Hi-5 Cells

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Product Details

Purification tag / Conjugate: His tag

Purification: purified by chromatography

Application Details

Comment:

Synonyms: Early secretory antigenic target, 6 kDa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: ESAT6

Alternative Name: CDC1551 ESAT6

Background: ESAT6, the 6 kDa early secretory antigenic target of Mycobacterium tuberculosis, is a secretory protein and potent T cell antigen. ESAT6 has been shown to directly bind to the TLR2 receptor, inhibiting downstream signal transduction. Recently it was shown that ESAT6 is very potential as diagnostic for differentiation between the mycobacterial infection and BCG vaccination. Recombinant Mycobacterium tuberculosis CDC1551 ESAT6 protein, fused to His-tag at C-terminus, was expressed in Baculovirus and purified by using conventional chromatography techniques.

Molecular Weight: 11 kDa (104aa)

NCBI Accession: NP_338543