SH3G2 Protein (His tag)
Quick Overview for SH3G2 Protein (His tag) (ABIN1098256)
Target
See all SH3G2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This SH3G2 protein is labelled with His tag.
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Purification
- purified by chromatography
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Endophilin-A1 (SH3G2) (AA 1-352) protein (His tag)
custom-made SH3G2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Endophilin-A1 (SH3G2) (AA 1-352) protein (His tag)custom-made SH3G2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Endophilin-A1 (SH3G2) (AA 1-352) protein (His-IF2DI Tag)SH3G2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB
Endophilin-A1 (SH3G2) (AA 1-279) protein (GST tag)SH3G2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Endophilin-A1 (SH3G2) (AA 1-352) protein (GST tag)SH3G2 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Endophilin-A1 (SH3G2) protein (DYKDDDDK Tag)SH3G2 Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Endophilin-A1 (SH3G2) protein (Myc-DYKDDDDK Tag)SH3G2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Comment
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Synonyms: Endophilin-A1, CNSA2, EEN-B1, SH3D2A, SH3P4
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl
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Storage
- 4 °C
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Storage Comment
- Avoid repeated freezing and thawing cycles.
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- SH3G2 (Endophilin-A1 (SH3G2))
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Alternative Name
- SH3GL2
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Background
- SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. Recombinant human SH3GL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 42.5 kDa (376aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_003017
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Pathways
- Neurotrophin Signaling Pathway, EGFR Downregulation
Target
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