CLTA Protein (His tag)
Quick Overview for CLTA Protein (His tag) (ABIN1098291)
Target
See all CLTA ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CLTA protein is labelled with His tag.
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Purification
- purified by chromatography
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Comment
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Synonyms: Clathrin, light chain A, LCA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 10% glycerol
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Storage
- 4 °C
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Storage Comment
- Avoid repeated freezing and thawing cycles.
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- CLTA (Clathrin, Light Chain A (CLTA))
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Alternative Name
- CLTA
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Background
- Clathrin, light chain A, also known as CLTA, belongs to the clathrin family. Clathrin is a large, soluble protein composed of heavy and light chains. It is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are captured by Clathrin-coated vesicles. CLTA is one of two clathrin light chain proteins which are believed to function as regulatory elements. Recombinant human CLTA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 26.2 kDa (242aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
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NCBI Accession
- NP_001824
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
Target
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