MVK Protein (His tag)
Quick Overview for MVK Protein (His tag) (ABIN1098525)
Target
See all MVK ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This MVK protein is labelled with His tag.
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Purification
- purified by chromatography
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Mevalonate Kinase (MVK) (AA 1-395) protein (His tag)
custom-made MVK Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mevalonate Kinase (MVK) (AA 1-396) protein (His tag)custom-made MVK Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mevalonate Kinase (MVK) (AA 1-396) protein (GST tag)MVK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Mevalonate Kinase (MVK) protein (GST tag,His tag)MVK Origin: Human Host: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE.
Mevalonate Kinase (MVK) proteinMVK Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS
Mevalonate Kinase (MVK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MVK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Mevalonate Kinase (MVK) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)MVK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Comment
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Synonyms: Mevalonate kinase, LRBP, MK, MVLK
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
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Storage
- 4 °C
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Storage Comment
- Avoid repeated freezing and thawing cycles.
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- MVK (Mevalonate Kinase (MVK))
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Alternative Name
- MVK
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Background
- Mevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive,hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Recombinant human MVK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Molecular Weight
- 44.8 kDa (419aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_001107657
Target
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