MFAP2 Protein (AA 18-183) (His tag)
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- Target See all MFAP2 Proteins
- MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 18-183
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MFAP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMQGQYDL DPLPPFPDHV QYTHYSDQID NPDYYDYQEV TPRPSEEQFQ FQSQQQVQQE VIPAPTPEPG NAELEPTEPG PLDCREEQYP CTRLYSIHRP CKQCLNEVCF YSLRRVYVIN KEICVRTVCA HEELLRADLC RDKFSKCGVM ASSGLCQSVA ASCARSCGSC
- Purity
- > 85% by SDS-PAGE
- Top Product
- Discover our top product MFAP2 Protein
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Microfibrillar Associated Protein 2 (MFAP2) (AA 76-158) protein (GST tag)
MFAP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Microfibrillar Associated Protein 2 (MFAP2) (AA 6-162) (Active) protein (His tag)MFAP2 Origin: Human Host: Escherichia coli (E. coli) > 95 % AcA, CC Active
Microfibrillar Associated Protein 2 (MFAP2) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MFAP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Microfibrillar Associated Protein 2 (MFAP2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)MFAP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Microfibrillar Associated Protein 2 (MFAP2) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)MFAP2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 M Urea, 20% glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Target
- MFAP2 (Microfibrillar Associated Protein 2 (MFAP2))
- Alternative Name
- MAGP-1/MFAP2 (MFAP2 Products)
- Background
- Microfibrillar-associated protein 2, also known as MFAP2, is an O-glycosylated protein secreted to the extracellular space and the extracellular matrix. MFAP2 associates with biglycan and elastin in a ternary complex. It is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta. Recombinant human MFAP2, fused to His-tag at N-terminus, was expressed in E. coli.
- Molecular Weight
- 21.5 kDa (190aa)
- NCBI Accession
- NP_002394
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