RASSF1 Protein (His tag)

Catalog No. ABIN1098704

This Recombinant RASSF1 protein is produced in Escherichia coli (E. coli).

Quick Overview for RASSF1 Protein (His tag) (ABIN1098704)

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Purity: > 85 % by SDS - PAGE

Product Details

Purification tag / Conjugate: This RASSF1 protein is labelled with His tag.

Application Details

Comment:

Synonyms: Ras association domain-containing protein 1, 123F2, NORE2A, RASSF1, RDA32, REH3P21

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Alternative Name: RASSF1A

Background: RASSF1A is similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. This protein required for death receptor-dependent apoptosis. Recombinant human RASSF1A protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 42.9 kDa (376aa)

NCBI Accession: NP_009113