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CD2 Protein (CD2) (His tag)

This Recombinant CD2 protein is produced in Escherichia coli (E. coli).
Catalog No. ABIN1098728

Quick Overview for CD2 Protein (CD2) (His tag) (ABIN1098728)

Target

See all CD2 Proteins
CD2

Protein Type

Recombinant

Origin

  • 15
  • 3
  • 2
  • 1
  • 1
Human

Source

  • 11
  • 6
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Purity

> 85 % by SDS - PAGE
  • Purification tag / Conjugate

    This CD2 protein is labelled with His tag.
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  • Comment

    Synonyms: T-cell surface antigen CD2, SRBC, T11

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/ml (determined by Bradford assay)

    Buffer

    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea

    Storage

    4 °C

    Storage Comment

    Avoid repeated freezing and thawing cycles.
  • Target

    CD2

    Alternative Name

    CD2

    Background

    CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant human CD2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

    Molecular Weight

    23.8 kDa (209aa)

    NCBI Accession

    NP_001758
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