CD2 Protein (CD2) (His tag)
Quick Overview for CD2 Protein (CD2) (His tag) (ABIN1098728)
Target
See all CD2 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This CD2 protein is labelled with His tag.
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Comment
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Synonyms: T-cell surface antigen CD2, SRBC, T11
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea
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Storage
- 4 °C
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Storage Comment
- Avoid repeated freezing and thawing cycles.
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- CD2
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Alternative Name
- CD2
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Background
- CD2, also known as T-cell surface antigen T11/Leu-5, is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3/CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections. The great majority of T cell lymphomas and leukaemias also express CD2, making it possible to use the presence of the antigen to distinguish these conditions from B cell neoplasms. Recombinant human CD2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
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Molecular Weight
- 23.8 kDa (209aa)
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NCBI Accession
- NP_001758
Target
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