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HMGB2 Protein

This HMGB2 protein is expressed in .
Catalog No. ABIN1176832

Quick Overview for HMGB2 Protein (ABIN1176832)

Target

See all HMGB2 Proteins
HMGB2 (High Mobility Group Box 2 (HMGB2))

Biological Activity

Active

Origin

  • 12
  • 3
  • 1
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  • 1
Human

Host

Please inquire

Application

Activation (Act), Cellular Assay (CA)

Purity

> 95 %
  • Sequence

    MGKGDPNKPR GKMSSYAFFV QTCREEHKKK HPDSSVNFAE FSKKCSERWK TMSAKEKSKF EDMAKSDKAR YDREMKNYVP PKGDKKGKKK DPNAPKRPPS AFFLFCSEHR PKIKSEHPGL SIGDTAKKLG EMWSEQSAKD KQPYEQKAAK LKEKYEKDIA AYRAKGKSEA GKKGPGRPTG SKKKNEPEDE EEEEE

    Characteristics

    The sequence of this product is that of Homo sapiens. It contains only trace amounts of LPS (<0.4 ng/mg protein) and it is tested for the ability to induce fibroblast migration. This product has been tested for activity in a cell migration assay. Maximal activity in the cell migration assay is obtained at 1 nM, or 25 ng/ml.

    Purification

    Purified

    Endotoxin Level

    The purified protein is free from LPS (Cambrex Limulus Amoebocyte Assay QCL-1000, < 0.4 ng LPS per mg protein).
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  • Restrictions

    For Research Use only
  • Buffer

    50 mM HEPES buffer pH 7.9, 500 mM NaCl, 0.5 mM DTT

    Handling Advice

    The product is provided frozen. Repeated freezing and thawing is not recommended.

    Storage

    -20 °C
  • Target

    HMGB2 (High Mobility Group Box 2 (HMGB2))

    Alternative Name

    High-mobility group protein B2 (HMGB2)

    Background

    HMGB2 is 80% identical to HMGB1 protein, but is encoded by a different gene. It consists of 195 amino acids and has a calculated molecular mass of approximately 22.3 kDa.

    Molecular Weight

    approximately 22.3 kDa

    Pathways

    Cellular Response to Molecule of Bacterial Origin
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