PSMD4/ASF Protein (AA 2-377)
Quick Overview for PSMD4/ASF Protein (AA 2-377) (ABIN1343997)
Target
See all PSMD4/ASF (Psmd4) ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 2-377
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Purpose
- Angiocidin (human) (rec.) (untagged)
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Cross-Reactivity
- Human
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Characteristics
- Human angiocidin (aa 2-377) is untagged.
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Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) (AA 1-376) protein (His tag)
custom-made Psmd4 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) (AA 1-377) protein (His tag)custom-made Psmd4 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) (AA 1-377) protein (GST tag)Psmd4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4) protein (Myc-DYKDDDDK Tag)Psmd4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with 100 μL sterile water.
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Concentration
- 0.1 mg/mL
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Buffer
- Contains PBS.
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Handling Advice
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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Expiry Date
- 6 months
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- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
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Alternative Name
- Angiocidin
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Background
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PSMD4, 26S Proteasome Regulatory Subunit S5A, Rpn10, Multiubiquitin Chain-binding Protein, Antisecretory Factor 1, 26S Proteasome Non-ATPase Regulatory Subunit 4
Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and alpha2beta1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.
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Molecular Weight
- ~50kDa (SDS-PAGE)
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UniProt
- P55036
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
Target
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