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Resistin Protein (RETN) (AA 21-114) (DYKDDDDK Tag)

This Recombinant Resistin protein is produced in HEK-293 Cells. There is 1 publication available.
Catalog No. ABIN1344359

Quick Overview for Resistin Protein (RETN) (AA 21-114) (DYKDDDDK Tag) (ABIN1344359)

Target

See all Resistin (RETN) Proteins
Resistin (RETN)

Protein Type

Recombinant

Origin

  • 19
  • 6
  • 4
  • 3
  • 1
Mouse

Source

  • 20
  • 7
  • 1
  • 1
HEK-293 Cells

Application

SDS-PAGE (SDS)

Purity

>90 % (SDS-PAGE)
  • Protein Characteristics

    AA 21-114

    Purification tag / Conjugate

    This Resistin protein is labelled with DYKDDDDK Tag.

    Purpose

    Resistin (mouse) (rec.)

    Cross-Reactivity

    Mouse

    Characteristics

    Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG®-tag.

    Sterility

    Sterile filtered

    Endotoxin Level

    <0.1EU/μg purified protein (LAL test).
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.4 mg/mL

    Buffer

    0.2μm-filtered solution in PBS, pH 7.2.

    Handling Advice

    After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

    Storage

    4 °C,-20 °C

    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

    Expiry Date

    6 months
  • Daquinag, Zhang, Amaya-Manzanares, Simmons, Kolonin: "An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).

  • Target

    Resistin (RETN)

    Alternative Name

    Resistin

    Background

    FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor

    The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

    Molecular Weight

    ~15kDa (SDS-PAGE)

    UniProt

    Q99P87

    Pathways

    Feeding Behaviour, Smooth Muscle Cell Migration
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