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Resistin Protein (RETN) (AA 21-114) (DYKDDDDK Tag)

RETN Origin: Mouse Host: HEK-293 Cells Recombinant >90 % (SDS-PAGE) SDS
Catalog No. ABIN1344359
  • Target See all Resistin (RETN) Proteins
    Resistin (RETN)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-114
    Origin
    • 18
    • 6
    • 4
    • 3
    • 1
    Mouse
    Source
    • 20
    • 6
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Resistin protein is labelled with DYKDDDDK Tag.
    Application
    SDS-PAGE (SDS)
    Purpose
    Resistin (mouse) (rec.)
    Cross-Reactivity
    Mouse
    Characteristics
    Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG®-tag.
    Purity
    >90 % (SDS-PAGE)
    Sterility
    Sterile filtered
    Endotoxin Level
    <0.1EU/μg purified protein (LAL test).
    Top Product
    Discover our top product RETN Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.4 mg/mL
    Buffer
    0.2μm-filtered solution in PBS, pH 7.2.
    Handling Advice
    After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
    Storage
    4 °C,-20 °C
    Storage Comment

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

    Expiry Date
    6 months
  • Daquinag, Zhang, Amaya-Manzanares, Simmons, Kolonin: "An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).

  • Target
    Resistin (RETN)
    Alternative Name
    Resistin (RETN Products)
    Background

    FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor

    The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.

    Molecular Weight
    ~15kDa (SDS-PAGE)
    UniProt
    Q99P87
    Pathways
    Feeding Behaviour, Smooth Muscle Cell Migration
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