Resistin Protein (RETN) (AA 21-114) (DYKDDDDK Tag)
-
- Target See all Resistin (RETN) Proteins
- Resistin (RETN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-114
-
Origin
- Mouse
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Resistin protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Purpose
- Resistin (mouse) (rec.)
- Cross-Reactivity
- Mouse
- Characteristics
- Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- Sterile filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product RETN Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.4 mg/mL
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.2.
- Handling Advice
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
-
-
An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).
: "
-
An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).
-
- Target
- Resistin (RETN)
- Alternative Name
- Resistin (RETN Products)
- Background
-
FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
- Molecular Weight
- ~15kDa (SDS-PAGE)
- UniProt
- Q99P87
- Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
-