CXCL16 Protein (AA 27-201, C-Term)

Catalog No. ABIN1691538

This Recombinant CXCL16 protein is expressed in Human Cells.

Quick Overview for CXCL16 Protein (AA 27-201, C-Term) (ABIN1691538)

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Protein Type: Recombinant

Origin: Mouse

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: C-Term, AA 27-201

Purpose: Recombinant Mouse IL-17A

Sequence: NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLPQA STQTPEAAEG TPSDTSTPAH SQSTQHSTLP SGALSLNKEH TQPWEMTTLP SGYGLEARPE AEANEKQQDD RQQEAPGAGA STPAWVDHHH HHH

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Alternative Name: CXCL16

Background: Recombinant Mouse C-X-C Motif Chemokine 16/CXCL16 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asn27-Trp201) of Human CXCL16 fused with a polyhistidine tag at the C-terminus.
CXCL16 is a single-pass type I membrane protein, which consists of 246 AAs, CXCL16 induces a strong chemotatic response and calcium mobilization. CXCL16 acts as a scavenger receptor on macrophages, which specially binds to oxidized low density lipoprotein. CXCL16 may involves in pathophysiology such as atherogenesis. Soluble CXCL16 may play an important role in liver metastases through the induction of epithelial-mesenchymal transition.

Molecular Weight: 16.2 kDa

UniProt: Q62386