Syntaxin 6 Protein (STX6) (AA 2-234)

Catalog No. ABIN1691986

This Recombinant Syntaxin 6 protein is produced in Escherichia coli (E. coli).

Quick Overview for Syntaxin 6 Protein (STX6) (AA 2-234) (ABIN1691986)

Target: Syntaxin 6 (STX6)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 2-234

Purpose: Recombinant Human Syntaxin-6/STX6

Sequence: SMEDPFFVVK GEVQKAVNTA QGLFQRWTEL LQDPSTATRE EIDWTTNELR NNLRSIEWDL EDLDETISIV EANPRKFNLD ATELSIRKAF ITSTRQVVRD MKDQMSTSSV QALAERKNRQ ALLGDSGSQN WSTGTTDKYG RLDRELQRAN SHFIEEQQAQ QQLIVEQQDE QLELVSGSIG VLKNMSQRIG GELEEQAVML EDFSHELEST QSRLDNVMKK LAKVSHMTSD RRQ

Characteristics: Recombinant Human Syntaxin-6/STX6 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Gln234) of Human STX6.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Syntaxin 6 (STX6)

Alternative Name: STX6

Background: Syntaxin-6 (STX6) is a single-pass type IV membrane protein, which belongs to the Syntaxin family. STX6 is mainly localized in the plasma membrane. STX6 contains one t-SNARE coiled-coil homology domain and involved in intracellular vesicle trafficking. When STX6 function is inhibited, internalization through caveolae is dramaticaliy reduced, whereas other endocytic mechanisms are unaffected. It is reported that STX6 is necessary for proper expression of focal adhesion kinase and integrin alpha5 adhesion receptor.
Alternative Names: Syntaxin-6, STX6

Molecular Weight: 26.8 kDa

UniProt: O43752

Pathways: Synaptic Vesicle Exocytosis