SULT1A1 Protein (AA 1-295) (His tag)

Catalog No. ABIN1692225

Recombinant SULT1A1 protein expressed in Escherichia coli (E. coli).

Quick Overview for SULT1A1 Protein (AA 1-295) (His tag) (ABIN1692225)

Target: SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 1-295

Purification tag / Conjugate: This SULT1A1 protein is labelled with His tag.

Purpose: Recombinant Human Sulfotransferase 1A1/SULT1A1 (N-6His)

Sequence: MNHKVHHHHH HMELIQDTSR PPLEYVKGVP LIKYFAEALG PLQSFQARPD DLLISTYPKS GTTWVSQILD MIYQGGDLEK CHRAPIFMRV PFLEFKAPGI PSGMETLKDT PAPRLLKTHL PLALLPQTLL DQKVKVVYVA RNAKDVAVSY YHFYHMAKVH PEPGTWDSFL EKFMVGEVSY GSWYQHVQEW WELSRTHPVL YLFYEDMKEN PKREIQKILE FVGHSLPEET VDFVVQHTSF KEMKKNPMTN YTTVPQEFMD HSISPFMRKG MAGDWKTTFT VAQNERFDAD YAEKMAGCSL SFRSEL

Characteristics: Recombinant Human Sulfotransferase 1A1/SULT1A1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu295) of Human SULT1A1 fused with a His tag at the N-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl,1 mM EDTA, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: SULT1A1 (Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 (SULT1A1))

Alternative Name: SULT1A1

Sub Type: Fusionprotein

Background: Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver, lung, adrenal, brain, platelets, and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Alternative Names: Sulfotransferase 1A1, ST1A1, Aryl sulfotransferase 1, HAST1/HAST2, Phenol Sulfotransferase 1, Phenol-Sulfating Phenol Sulfotransferase 1, P-PST 1, ST1A3, Thermostable Phenol Sulfotransferase, Ts-PST, SULT1A1, STP, STP1, OK/SW-cl.88

Molecular Weight: 35.5 kDa

UniProt: P50225