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IL-33 Protein (AA 109-266)

IL33 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692487
  • Target See all IL-33 (IL33) Proteins
    IL-33 (IL33) (Interleukin 33 (IL33))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 109-266
    Origin
    • 22
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Source
    • 29
    • 12
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Mouse Interleukin-33/IL-33
    Sequence
    MSIQGTSLLT QSPASLSTYN DQSVSFVLEN GCYVINVDDS GKDQEQDQVL LRYYESPCPA SQSGDGVDGK KLMVNMSPIK DTDIWLHAND KDYSVELQRG DVSPPEQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEEKDESCN NIMFKLSKI
    Characteristics

    Recombinant Mouse Interleukin-33/IL-33

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IL33 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Alternative Name
    Interleukin-33/IL-33 (IL33 Products)
    Background
    Recombinant Mouse Interleukin-33/IL-33 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser109-Ile266) of Mouse IL-33.
    Mouse Interleukin 33 (IL-33) is a proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1. BindingIL-33 to this receptor activates NF-κB and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces the expression of IL-4, IL-5, IL-13 and also leads to severe pathological changes in mucosal organs.
    Molecular Weight
    17.6 kDa
    UniProt
    Q8BVZ5
    Pathways
    Production of Molecular Mediator of Immune Response
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