Cytokeratin 19 Protein
Quick Overview for Cytokeratin 19 Protein (ABIN1880333)
Target
See all Cytokeratin 19 (KRT19) ProteinsProtein Type
Origin
Source
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Purification
- Purified
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Keratin 19 (KRT19) (AA 1-403) protein (His tag)
custom-made KRT19 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Keratin 19 (KRT19) (AA 1-400) protein (His tag)custom-made KRT19 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Keratin 19 (KRT19) (AA 310-399) protein (His tag)KRT19 Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Keratin 19 (KRT19) (AA 1-400) protein (GST tag)KRT19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris-HCl (pH 7.4 +/- 0.2) with 0.2 % NaN3.
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Preservative
- Sodium azide
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Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Storage
- 4 °C
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Alternative Name
- Cytokeratin 19
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Background
- Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have diagnostic use and prognostic significance in some types of human malignancy. Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate diagnosis of papillary carcinoma than the other combinations.
Target
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