Osteopontin Protein
Quick Overview for Osteopontin Protein (ABIN1880427)
Target
See all Osteopontin (SPP1) ProteinsProtein Type
Origin
Source
Purity
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Buffer
 - 10 mM Tris-HCl (pH 7.4 +/- 0.2) with 0.2 % NaN3.
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Preservative
 - Sodium azide
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Precaution of Use
 - WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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Storage
 - 4 °C
 
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- Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))
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Alternative Name
 - Osteopontin
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Background
 - Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), secreted phosphoprotein 1 (SPP1), is a human gene product. The gene has 7 exons, spans 5 kilobases in length and in humans it is located on 4q13. The protein is composed of ~300 amino acids residues and has ~30 carbohydrate residues attached including 10 sialic acid residues, which are attached to the protein during post-translational modification in the Golgi apparatus. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones.
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Molecular Weight
 - 35 kDa
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Pathways
 - Regulation of Cell Size
 
Target
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