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ADIPOQ Protein (AA 21-247)

ADIPOQ Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2017655
  • Target See all ADIPOQ Proteins
    ADIPOQ (Adiponectin (ADIPOQ))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 21-247
    Origin
    • 25
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse
    Source
    • 32
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Characteristics
    ED50 < 5 μg/mL, measured by a cell growth inhibitory assay using M1 cells, corresponding to a specific activity of > 2x 10^2 units/mg.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant mouse Adiponectin (rmAdiponectin) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmAdiponectin remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    Expiry Date
    6 months
  • Target
    ADIPOQ (Adiponectin (ADIPOQ))
    Alternative Name
    Adiponectin (ADIPOQ Products)
    Background
    Adiponectin is a hormone mainly produced by adipocytes. Adiponectin forms a homotrimer and exists as higher order multimers in vivo. The receptors of Adiponectin are seven transmembrane G protein coupled receptors: Receptor 1 is expressed in skeletal muscle and Receptor 2 in liver. Adiponectin receives a lot of attention because of its anti-diabetic, anti-atherosclerotic, and anti-inflammatory properties. Adiponectin increases the expression of molecules involved in fatty acid transport, combustion of fatty acid, and energy dissipation, and increases insulin sensitivity of the body. Decreased levels of Adiponectin are associated with hypertension, cardiovascular diseases, and metabolic syndromes. Therefore, Adiponectin has promising potential as a pharmacological agent.Recombinant mouse Adiponectin (rmAdiponectin) produced in E. coli is a single non-glycosylated polypeptide chain containing 227 amino acids. A fully biologically active molecule, rmAdiponectin has a molecular mass of 24.6 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Acrp-30, GBP-28, Apm-1
    Molecular Weight
    24.6 kDa, observed by reducing SDS-PAGE.
    UniProt
    Q60994
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