ADIPOQ Protein (AA 19-244)
Quick Overview for ADIPOQ Protein (AA 19-244) (ABIN2017662)
Target
See all ADIPOQ ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 19-244
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Characteristics
- ED50 < 2 ng/mL, measured in a cell growth inhibition assay using M1 cells.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant Human Adiponectin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Adiponectinshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- ADIPOQ (Adiponectin (ADIPOQ))
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Alternative Name
- Adiponectin
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Background
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Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity. It is synthesized exclusively by adipocytes and secreted into plasma. It antagonizes THF-alpha by negatively regulating its expression. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin can form low molecular weight complexes (LMW), middle molecular weight complexes (MMW) and higher molecular weight complexes (HMW). These bind to various growth factors, such as HBEGF, PDGFB and FGF2, and play a role in cell growth, angiogenesis and tissue remodeling.
Synonyms: Acrp-30, GBP-28, Apm-1 -
Molecular Weight
- 25-28 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q15848
Target
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