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ADIPOQ Protein (AA 19-244)

Recombinant ADIPOQ protein expressed in CHO Cells.
Catalog No. ABIN2017662

Quick Overview for ADIPOQ Protein (AA 19-244) (ABIN2017662)

Target

See all ADIPOQ Proteins
ADIPOQ (Adiponectin (ADIPOQ))

Protein Type

Recombinant

Biological Activity

Active

Origin

  • 25
  • 19
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Source

  • 32
  • 12
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
CHO Cells

Purity

> 95 % as analyzed by SDS-PAGE and HPLC.
  • Protein Characteristics

    AA 19-244

    Characteristics

    ED50 < 2 ng/mL, measured in a cell growth inhibition assay using M1 cells.

    Endotoxin Level

    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Storage

    -80 °C

    Storage Comment

    Lyophilized recombinant Human Adiponectin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Adiponectinshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    Expiry Date

    6 months
  • Target

    ADIPOQ (Adiponectin (ADIPOQ))

    Alternative Name

    Adiponectin

    Background

    Adiponectin is an important adipokine involved in the control of fat metabolism and insulin sensitivity. It is synthesized exclusively by adipocytes and secreted into plasma. It antagonizes THF-alpha by negatively regulating its expression. It also inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin can form low molecular weight complexes (LMW), middle molecular weight complexes (MMW) and higher molecular weight complexes (HMW). These bind to various growth factors, such as HBEGF, PDGFB and FGF2, and play a role in cell growth, angiogenesis and tissue remodeling.
    Synonyms: Acrp-30, GBP-28, Apm-1

    Molecular Weight

    25-28 kDa, observed by reducing SDS-PAGE.

    UniProt

    Q15848
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